Atypical Endometrial Cells Post-menopause

Case Report

Authors

  • Ana Cardoso Polytechnic Institute of Porto
  • Diana Alves Polytechnic Institute of Porto
  • Paula Leite Local Health Unit of Matosinhos
  • Rute Dominguez Local Health Unit of Matosinhos

DOI:

https://doi.org/10.26537/citotech.v0i2.497

Keywords:

carcinosarcoma, atypical glandular cells, gynecological cytology, post-menopause, conventional cytology

Abstract

The presence of endometrial cells is considered an alarming finding in gynecological smears of women in the second half of the menstrual cycle or after the age of 45 years. In particular, in post- menopausal women, the presence of atypical endometrial cells may represent a serious uterine pathology and requires a thorough evaluation.
We report a case of a 77 year post-menopausal woman, who presented with vaginal bleeding without ecographic uterine alterations. Cervicovaginal cytology revealed the presence of abnormal endometrial cells in clusters, unusual in the clinical context of the woman. The cytological result was atypical glandular cells, favor neoplastic. Based on this result, the patient was submitted to an endometrial curettage, which was diagnosed as carcinosarcoma, and with a radical hysterectomy.
Although the cytological result was not in accordance with the histological diagnosis, it indicates the necessity of studying the endometrium and the subsequent diagnosis of carcinosarcoma.

Author Biographies

Ana Cardoso, Polytechnic Institute of Porto

School of Allied Health Technologies - Polytechnic Institute of Porto (ESTSP-IPP), Portugal

Diana Alves, Polytechnic Institute of Porto

School of Allied Health Technologies – Polytechnic Institute of Porto (ESTSP-IPP), Portugal

Paula Leite, Local Health Unit of Matosinhos

Pathology Department of Pedro Hispano Hospital, Local Health Unit of Matosinhos, Portugal

Rute Dominguez, Local Health Unit of Matosinhos

Pathology Department of Pedro Hispano Hospital, Local Health Unit of Matosinhos, Portugal

Published

2016-06:-16

How to Cite

Cardoso, A., Alves, D., Leite, P., & Dominguez, R. (2016). Atypical Endometrial Cells Post-menopause: Case Report. Citotech Online - Case Review, (2), 14–18. https://doi.org/10.26537/citotech.v0i2.497